http://localhost:8080/xmlui/handle/123456789/4091 2026-06-07T09:46:06Z http://localhost:8080/xmlui/handle/123456789/4489 Title: Effect of Ethanolic Extract of Spondias pinnata on IschemiaReperfusion Injury and Ischemic Preconditioning of Heart (Only Abstract) Authors: Kishore H; Kaur B; Kalsi V; Suttee, Ashish Abstract: Background and Purpose: Cardiac ischemic preconditioning represents the most powerful endogenous protective mechanism against ischemia. Spondias pinnata is rich source of flavonoids and phenolic compounds. The purpose of present study is to investigate the effect of ethanolic extract of stem bark of Spondias pinnata (100 mg/kg or 200 mg/kg) on ischemia- reperfusion injury and ischemic preconditioning of heart. Experimental Approach: Hearts from albino rats of Wistar strain were isolated and immediately mounted on Langendorff’s apparatus for retrograde perfusion. Myocardial ischemia reperfusion injury was produced by mounting isolated rat hearts on Langendorff’s apparatus and global ischemia was produced for 30 min followed by reperfusion for 120 min. In ischemic preconditioning group, the hearts were subjected to four episodes of 5 min ischemia and 5 min of reperfusion after 10 minutes of stabilization and then 30 min global ischemia, followed by 120 min of reperfusion. Myocardial infarct size was estimated macroscopically using TTC staining. The magnitude of cardiac injury was measured by Lactate Dehydrogenase (LDH) and Creatine Kinase (CK) concentration in the coronary effluent. The increase in infarct size and the release of LDH and CK are documented to be an index of I/R induced myocardial injury. Key Results: Spondias pinnata ethanolic extract significantly reduced ischemia reperfusioninduced myocardial injury in vitro, but it does not enhanced the cardioprotective effect of ischemic preconditioning. Conclusion and Implications: Administration of Spondias pinnata ethanolic extract may prevent ischemic and reperfusion induced myocardial injury probably by its antioxidant activity. 2016-01-05T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4488 Title: Phytochemical Investigation and Evaluation of Free Radical Scavenging Potential of Benincasa hispida Peel Extracts Authors: Rana, Siddhant; Suttee, Ashish Abstract: The crude extracts of Benincasa hispida i.e. Methanolic extract (M.E.) and aqueous extract (A.E.) were studied for the presence and detection of phytochemical such as alkaloids, saponins, steroids, carbohydrates and flavonoids using standard procedures. On the basis of the results, the extracts were further used for in vitro evaluation of antioxidant activity. The present study was designed to study the phytochemical screening and to investigate the free radical scavenging potential of aqueous and methanolic extract of dried ripe peels of Benincasa hispida. The free radical scavenging potential was evaluated by DPPH(1.1,-diphenyl-2-picrylhydrazyl). The extracts showed significant potential in a dose dependant manner when compared with the ascorbic acid. The highest scavenging activity of ME was found to be 87.87% at a concentration of 100µg mL1 and that of aqueous 86.5% at concentration of 100 µg mL-1 . Thus both the ME and AE may be useful as a natural antioxidants in the near future. 2012-07-05T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4487 Title: Evaluation of Antioxidant and Anthelmintic Properties of Caesalpinia sappan L. Leaves (Only Abstract) Authors: K Harjit; Mohamand, A H; Ashish, Suttee Abstract: Caesalpinia sappan L. is a popular medicinal plant known to both the Ayurveda and Chinese traditional medicines since ancient time. The aim of this research was to study the qualitative phytochemistry and to determine the antioxidant and anthelmintic activities of C. sappan leaves. Phytochemical analysis indicated the presence of various plant bioactive metabolites in C. sappan leaves. Different solvent extracts of the crude drug were tested for their in vitro antioxidant potential using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and ferricion-reducing antioxidant power (FRAP) assay. Total phenolic content (TPC) and total flavonoids content (TFC) of the extracts were determined by spectrophotometric method. Methanol extract and ethyl acetate extract of the leaves were evaluated for anthelmintic activity against earthworms (Eisenia fetida). Results of this study revealed that C. sappan leaves methanolic extract has significant antioxidant potential as compared with standard, vitamin C. Methanol extract also exhibited potent anthelmintic activity with paralysis time (19.13±0.340 min) and death time (54.21±0.533 min). These activities are attributed to the complex chemical nature of C. sappan leaves. The result of present study revealed that C. sappan leaves can serve as a good natural source of potent antioxidants and anthelminthiasis medicines. As per our extent of information, C. sappan leaves anthelmintic activity is reported for the first time in this paper. Further works are required for identification of phytochemicals and studying in vivo pharmacological activities of C. sappan leaves. 2016-01-31T00:00:00Z http://localhost:8080/xmlui/handle/123456789/4486 Title: Real Time Computer Vision Systems for Rice Kernels (Only Abstract) Authors: Verma, Bhupinder; Kaur, Gurpreet 2016-12-30T00:00:00Z